Sex differences in adult mood and in stress-induced transcriptional coherence across mesocorticolimbic circuitry

Women are approximately two times as likely to be diagnosed with major depressive disorder (MDD) compared to men. While sex differences in MDD might be driven by circulating gonadal hormones, we hypothesized that developmental hormone exposure and/or genetic sex might play a role. Mice were gonadect...

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Udgivet i:Transl Psychiatry
Main Authors: Paden, William, Barko, Kelly, Puralewski, Rachel, Cahill, Kelly M., Huo, Zhiguang, Shelton, Micah A., Tseng, George C., Logan, Ryan W., Seney, Marianne L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026087/
https://ncbi.nlm.nih.gov/pubmed/32066699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-0742-9
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