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Improved identification of concordant and discordant gene expression signatures using an updated rank-rank hypergeometric overlap approach

Recent advances in large-scale gene expression profiling necessitate concurrent development of biostatistical approaches to reveal meaningful biological relationships. Most analyses rely on significance thresholds for identifying differentially expressed genes. We use an approach to compare gene exp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cahill, Kelly M., Huo, Zhiguang, Tseng, George C., Logan, Ryan W., Seney, Marianne L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018631/
https://ncbi.nlm.nih.gov/pubmed/29942049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27903-2
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