1,25-dihydroxy Vitamin D3 and Interleukin-6 Blockade Synergistically Regulate Rheumatoid Arthritis by Suppressing Interleukin-17 Production and Osteoclastogenesis

BACKGROUND: Immune cells express the vitamin (vit) D receptor, and vit D is a potent immune-modulator. A negative correlation between serum vit D levels and rheumatoid arthritis (RA) disease activity has been reported. Therefore, we aimed to investigate if the sufficient serum vit D level is helpful...

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Veröffentlicht in:J Korean Med Sci
Hauptverfasser: Kim, Haneul, Baek, Seungye, Hong, Seung-Min, Lee, Jaeseon, Jung, Seung Min, Lee, Jennifer, Cho, Mi-La, Kwok, Seung-Ki, Park, Sung-Hwan
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Academy of Medical Sciences 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025907/
https://ncbi.nlm.nih.gov/pubmed/32056400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2020.35.e40
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