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Alloimmunogenicity of an Isolated MHC Allele is Affected by the Context of MHC Mismatch in a Murine Model

BACKGROUND: Humoral alloimmunization to HLA can represent a barrier to solid organ transplantation, can lead to a refractory state in patients requiring platelet transfusion, and can also contribute to TRALI. While exposure to HLA mismatched cells/tissues are generally required for HLA alloimmunizat...

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Publicat a:Transfusion
Autors principals: Hudson, Krystalyn E., Wong, Andrea S.L., Richards, Amanda L., Kapp, Linda M., Zimring, James C.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025900/
https://ncbi.nlm.nih.gov/pubmed/30681727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.15109
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