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Antibodies to Senescent Antigen and C3 Are Not Required for Normal Red Blood Cell Lifespan in a Murine Model

Red blood cells (RBCs) have a well-defined lifespan, indicating a mechanism by which senescent cells of a certain age are removed from circulation. However, the specifics by which senescent cells are recognized and removed are poorly understood. There are multiple competing hypotheses for this proce...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hudson, Krystalyn E., de Wolski, Karen, Kapp, Linda M., Richards, Amanda L., Schniederjan, Matthew J., Zimring, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670101/
https://ncbi.nlm.nih.gov/pubmed/29163500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01425
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