Transcriptome reprogramming and myeloid skewing in haematopoietic stem and progenitor cells in systemic lupus erythematosus

OBJECTIVES: Haematopoietic stem and progenitor cells (HSPCs) are multipotent cells giving rise to both myeloid and lymphoid cell lineages. We reasoned that the aberrancies of immune cells in systemic lupus erythematosus (SLE) could be traced back to HSPCs. METHODS: A global gene expression map of bo...

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Bibliografiske detaljer
Udgivet i:Ann Rheum Dis
Main Authors: Grigoriou, Maria, Banos, Aggelos, Filia, Anastasia, Pavlidis, Pavlos, Giannouli, Stavroula, Karali, Vassiliki, Nikolopoulos, Dionysis, Pieta, Antigone, Bertsias, George, Verginis, Panayotis, Mitroulis, Ioannis, Boumpas, Dimitrios T
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2020
Fag:
Systemic Lupus Erythematosus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025734/
https://ncbi.nlm.nih.gov/pubmed/31780527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2019-215782
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