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Female mice heterozygous for creatine transporter deficiency show moderate cognitive deficits

Creatine transporter (CrT) deficiency (CTD) is an X-linked disorder characterized by intellectual disability and speech delay. There have been reports that show female carriers have clinical symptoms. We have created CrT knockout (CrT(−/y)) mice in which males show severe cognitive deficits as a mod...

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Detalhes bibliográficos
Publicado no:J Inherit Metab Dis
Main Authors: Hautman, Emily R., Kokenge, Amanda N., Udobi, Kenea C., Williams, Michael T., Vorhees, Charles V., Skelton, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025435/
https://ncbi.nlm.nih.gov/pubmed/23716276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10545-013-9619-x
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