Implications of Oxidative Stress and Cellular Senescence in Age-Related Thymus Involution

The human thymus is a primary lymphoepithelial organ which supports the production of self-tolerant T cells with competent and regulatory functions. Paradoxically, despite the crucial role that it exerts in T cell-mediated immunity and prevention of systemic autoimmunity, the thymus is the first org...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Barbouti, Alexandra, Vasileiou, Panagiotis V. S., Evangelou, Konstantinos, Vlasis, Konstantinos G., Papoudou-Bai, Alexandra, Gorgoulis, Vassilis G., Kanavaros, Panagiotis
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025075/
https://ncbi.nlm.nih.gov/pubmed/32089780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7986071
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