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Legionella pneumophila regulates the activity of UBE2N by deamidase‐mediated deubiquitination
The Legionella pneumophila effector MavC induces ubiquitination of the E2 ubiquitin‐conjugating enzyme UBE2N by transglutamination, thereby abolishing its function in the synthesis of K(63)‐type polyubiquitin chains. The inhibition of UBE2N activity creates a conundrum because this E2 enzyme is impo...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7024838/ https://ncbi.nlm.nih.gov/pubmed/31825121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102806 |
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