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Molecular Basis of Gut Microbiome-Associated Colorectal Cancer: A Synthetic Perspective

A significant challenge toward studies of the human microbiota involves establishing causal links between bacterial metabolites and human health and disease states. Certain strains of commensal Escherichia coli harbor the 54-kb clb gene cluster which codes for small molecules named precolibactins an...

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Publicado en:J Am Chem Soc
Main Authors: Healy, Alan R., Herzon, Seth B.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024635/
https://ncbi.nlm.nih.gov/pubmed/28949546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07807
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