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Synthesis of Oligonucleotides Containing 2′-N-alkylaminocarbonyl-2′-amino-LNA (2′-urea-LNA) Moieties Using Post-Synthetic Modification Strategy

The post-synthetic modification of an oligonucleotide is a powerful strategy for the synthesis of various analogs of the oligonucleotide, aiming to achieve the desired functions. In this study, we synthesized the thymidine phosphoramidite of 2′-N-pentafluorophenoxycarbonyl-2′-amino-LNA, which was in...

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Dettagli Bibliografici
Pubblicato in:Molecules
Autori principali: Yamashita, Shoko, Nishida, Kodai, Osawa, Takashi, Nakanishi, Ayumi, Ito, Yuta, Hari, Yoshiyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024358/
https://ncbi.nlm.nih.gov/pubmed/31952133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25020346
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