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The effect of human gene therapy for RPE65-associated Leber’s congenital amaurosis on visual function: a systematic review and meta-analysis

BACKGROUND: RPE65-associated LCA (RPE65-LCA) is an inherited retinal degeneration caused by the mutations of RPE65 gene and gene therapy has been developed to be a promising treatment. This study aims to evaluate the association between changes in visual function and application of gene therapy in p...

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Bibliografske podrobnosti
izdano v:Orphanet J Rare Dis
Main Authors: Wang, Xue, Yu, Chaofeng, Tzekov, Radouil T., Zhu, Yihua, Li, Wensheng
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023818/
https://ncbi.nlm.nih.gov/pubmed/32059734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-020-1304-1
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