Stability and Compatibility Studies of Levothyroxine Sodium in Solid Binary Systems—Instrumental Screening

The influence of excipients on the stability of sodium levothyroxine pentahydrate (LTSS) under ambient conditions and thermal stress was evaluated. Since LTSS is a synthetic hormone with a narrow therapeutic index, the interactions of LTSS with excipients can lead to a drastic diminution of therapeu...

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Foilsithe in:Pharmaceutics
Main Authors: Ledeți, Ionuț, Romanescu, Mirabela, Cîrcioban, Denisa, Ledeți, Adriana, Vlase, Gabriela, Vlase, Titus, Suciu, Oana, Murariu, Marius, Olariu, Sorin, Matusz, Petru, Buda, Valentina, Piciu, Doina
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022666/
https://ncbi.nlm.nih.gov/pubmed/31936742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12010058
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