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Stability and Compatibility Studies of Levothyroxine Sodium in Solid Binary Systems—Instrumental Screening

The influence of excipients on the stability of sodium levothyroxine pentahydrate (LTSS) under ambient conditions and thermal stress was evaluated. Since LTSS is a synthetic hormone with a narrow therapeutic index, the interactions of LTSS with excipients can lead to a drastic diminution of therapeu...

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Ledeți, Ionuț, Romanescu, Mirabela, Cîrcioban, Denisa, Ledeți, Adriana, Vlase, Gabriela, Vlase, Titus, Suciu, Oana, Murariu, Marius, Olariu, Sorin, Matusz, Petru, Buda, Valentina, Piciu, Doina
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022666/
https://ncbi.nlm.nih.gov/pubmed/31936742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12010058
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