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Stability and Compatibility Studies of Levothyroxine Sodium in Solid Binary Systems—Instrumental Screening

The influence of excipients on the stability of sodium levothyroxine pentahydrate (LTSS) under ambient conditions and thermal stress was evaluated. Since LTSS is a synthetic hormone with a narrow therapeutic index, the interactions of LTSS with excipients can lead to a drastic diminution of therapeu...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Ledeți, Ionuț, Romanescu, Mirabela, Cîrcioban, Denisa, Ledeți, Adriana, Vlase, Gabriela, Vlase, Titus, Suciu, Oana, Murariu, Marius, Olariu, Sorin, Matusz, Petru, Buda, Valentina, Piciu, Doina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022666/
https://ncbi.nlm.nih.gov/pubmed/31936742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12010058
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