Stability and Compatibility Studies of Levothyroxine Sodium in Solid Binary Systems—Instrumental Screening

The influence of excipients on the stability of sodium levothyroxine pentahydrate (LTSS) under ambient conditions and thermal stress was evaluated. Since LTSS is a synthetic hormone with a narrow therapeutic index, the interactions of LTSS with excipients can lead to a drastic diminution of therapeu...

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Gepubliceerd in:Pharmaceutics
Hoofdauteurs: Ledeți, Ionuț, Romanescu, Mirabela, Cîrcioban, Denisa, Ledeți, Adriana, Vlase, Gabriela, Vlase, Titus, Suciu, Oana, Murariu, Marius, Olariu, Sorin, Matusz, Petru, Buda, Valentina, Piciu, Doina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022666/
https://ncbi.nlm.nih.gov/pubmed/31936742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12010058
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