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Challenges Faced with Small Molecular Modulators of Potassium Current Channel Isoform Kv1.5
The voltage-gated potassium channel Kv1.5, which mediates the cardiac ultra-rapid delayed-rectifier (I(Kur)) current in human cells, has a crucial role in atrial fibrillation. Therefore, the design of selective Kv1.5 modulators is essential for the treatment of pathophysiological conditions involvin...
Shranjeno v:
| izdano v: | Biomolecules |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7022446/ https://ncbi.nlm.nih.gov/pubmed/31861703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10010010 |
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