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Mechanism and Improved Dissolution of Glycyrrhetinic Acid Solid Dispersion by Alkalizers
The purpose of this study was to increase the dissolution of glycyrrhetinic acid (GA) by preparing ternary solid dispersion (TSD) systems containing alkalizers, and to explore the modulating mechanism of alkalizers in solid dispersion systems. GA TSDs were prepared by hot melt extrusion (HME) with K...
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| Gepubliceerd in: | Pharmaceutics |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
MDPI
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7022421/ https://ncbi.nlm.nih.gov/pubmed/31968604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12010082 |
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