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Dissolution Improvement of Electrospun Nanofiber-Based Solid Dispersions for Acetaminophen

The objective of the present investigation was to prepare novel solid dispersions (SDs) of poorly water-soluble drugs with special microstructural characteristics using electrospinning process. With the hydrophilic polymer polyvinylpyrrolidone as the filament-forming polymer and acetaminophen (APAP)...

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Detalhes bibliográficos
Main Authors: Yu, Deng-Guang, Branford-White, Christopher, White, Kenneth, Li, Xue-Lian, Zhu, Li-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902305/
https://ncbi.nlm.nih.gov/pubmed/20446072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9438-4
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