Endoplasmic Reticulum (ER) Reorganization and Intracellular Retention of CD58 Are Functionally Independent Properties of the Human Cytomegalovirus ER-Resident Glycoprotein UL148

The human cytomegalovirus (HCMV) endoplasmic reticulum (ER)-resident glycoprotein UL148 is posited to play roles in immune evasion and regulation of viral cell tropism. UL148 prevents cell surface presentation of the immune cell costimulatory ligand CD58 while promoting maturation and virion incorpo...

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Vydáno v:J Virol
Hlavní autoři: Nguyen, Christopher C., Domma, Anthony J., Zhang, Hongbo, Kamil, Jeremy P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022370/
https://ncbi.nlm.nih.gov/pubmed/31801856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01435-19
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