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RNA Polymerase II Promoter-Proximal Pausing and Release to Elongation Are Key Steps Regulating Herpes Simplex Virus 1 Transcription
Herpes simplex virus 1 (HSV-1) genes are transcribed by cellular RNA polymerase II (Pol II). Expression of viral immediate early (α) genes is followed sequentially by early (β), late (γ(1)), and true late (γ(2)) genes. We used precision nuclear run-on with deep sequencing to map and to quantify Pol...
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| Udgivet i: | J Virol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7022368/ https://ncbi.nlm.nih.gov/pubmed/31826988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02035-19 |
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