A MUC16 IgG Binding Activity Selects for a Restricted Subset of IgG Enriched for Certain Simian Immunodeficiency Virus Epitope Specificities

We have recently shown that MUC16, a component of the glycocalyx of some mucosal barriers, has elevated binding to the G0 glycoform of the Fc portion of IgG. Therefore, IgG from patients chronically infected with human immunodeficiency virus (HIV), who typically exhibit increased amounts of G0 glyco...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Schneider, Jeffrey R., Shen, Xiaoying, Orlandi, Chiara, Nyanhete, Tinashe, Sawant, Sheetal, Carias, Ann M., Smith, Archer D., Kelleher, Neil L., Veazey, Ronald S., Lewis, George K., Tomaras, Georgia D., Hope, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022352/
https://ncbi.nlm.nih.gov/pubmed/31776284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01246-19
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