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Targeting Kaposi's Sarcoma-Associated Herpesvirus ORF21 Tyrosine Kinase and Viral Lytic Reactivation by Tyrosine Kinase Inhibitors Approved for Clinical Use

Kaposi’s sarcoma-associated herpesvirus (KSHV) is the cause of three human malignancies: Kaposi’s sarcoma, primary effusion lymphoma, and the plasma cell variant of multicentric Castleman disease. Previous research has shown that several cellular tyrosine kinases play crucial roles during several st...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Beauclair, Guillaume, Naimo, Eleonora, Dubich, Tatyana, Rückert, Jessica, Koch, Sandra, Dhingra, Akshay, Wirth, Dagmar, Schulz, Thomas F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022342/
https://ncbi.nlm.nih.gov/pubmed/31826996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01791-19
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