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Orchestration of human macrophage NLRP3 inflammasome activation by Staphylococcus aureus extracellular vesicles

Release of extracellular vesicles (EVs) is a common feature among eukaryotes, archaea, and bacteria. However, the biogenesis and downstream biological effects of EVs released from gram-positive bacteria remain poorly characterized. Here, we report that EVs purified from a community-associated methic...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Wang, Xiaogang, Eagen, William J., Lee, Jean C.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022218/
https://ncbi.nlm.nih.gov/pubmed/31988111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915829117
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