Fosfomycin Protects Mice From Staphylococcus aureus Pneumonia Caused by α-Hemolysin in Extracellular Vesicles by Inhibiting MAPK-Regulated NLRP3 Inflammasomes

α-Hemolysin (Hla) is a significant virulence factor in Staphylococcus aureus (S. aureus)-caused infectious diseases such as pneumonia. Thus, to prevent the production of Hla when treating S. aureus infection, it is necessary to choose an antibiotic with good antibacterial activity and effect. In our...

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Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: An, Yanan, Wang, Yang, Zhan, Jiuyu, Tang, Xudong, Shen, Keshu, Shen, Fengge, Wang, Chao, Luan, Wenjing, Wang, Xuefei, Wang, Xueyan, Liu, Mingyuan, Zheng, Qingchuan, Yu, Lu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Cellular and Infection Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644418/
https://ncbi.nlm.nih.gov/pubmed/31380296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00253
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