ECM1 is an essential factor for the determination of M1 macrophage polarization in IBD in response to LPS stimulation

Inflammatory bowel disease (IBD) comprises chronic relapsing disorders of the gastrointestinal tract characterized pathologically by intestinal inflammation and epithelial injury. Here, we uncover a function of extracellular matrix protein 1 (ECM1) in promoting the pathogenesis of human and mouse IB...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Zhang, Yaguang, Li, Xuezhen, Luo, Zhongguang, Ma, Liyan, Zhu, Songling, Wang, Zhishuo, Wen, Jing, Cheng, Shipeng, Gu, Wangpeng, Lian, Qiaoshi, Zhao, Xinhao, Fan, Weiguo, Ling, Zhiyang, Ye, Jing, Zheng, Songguo, Li, Dangsheng, Wang, Hongyan, Liu, Jie, Sun, Bing
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022174/
https://ncbi.nlm.nih.gov/pubmed/31980528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912774117
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