ECM1 is an essential factor for the determination of M1 macrophage polarization in IBD in response to LPS stimulation

Inflammatory bowel disease (IBD) comprises chronic relapsing disorders of the gastrointestinal tract characterized pathologically by intestinal inflammation and epithelial injury. Here, we uncover a function of extracellular matrix protein 1 (ECM1) in promoting the pathogenesis of human and mouse IB...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Zhang, Yaguang, Li, Xuezhen, Luo, Zhongguang, Ma, Liyan, Zhu, Songling, Wang, Zhishuo, Wen, Jing, Cheng, Shipeng, Gu, Wangpeng, Lian, Qiaoshi, Zhao, Xinhao, Fan, Weiguo, Ling, Zhiyang, Ye, Jing, Zheng, Songguo, Li, Dangsheng, Wang, Hongyan, Liu, Jie, Sun, Bing
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2020
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022174/
https://ncbi.nlm.nih.gov/pubmed/31980528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912774117
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