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Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma

Predicting the outcome of immunotherapy treatment in melanoma patients is challenging. Alterations in genes involved in antigen presentation and the interferon gamma (IFNγ) pathway play an important role in the immune response to tumors. We describe here that the overexpression of PSMB8 and PSMB9, t...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Kalaora, Shelly, Lee, Joo Sang, Barnea, Eilon, Levy, Ronen, Greenberg, Polina, Alon, Michal, Yagel, Gal, Bar Eli, Gitit, Oren, Roni, Peri, Aviyah, Patkar, Sushant, Bitton, Lital, Rosenberg, Steven A., Lotem, Michal, Levin, Yishai, Admon, Arie, Ruppin, Eytan, Samuels, Yardena
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021791/
https://ncbi.nlm.nih.gov/pubmed/32060274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14639-9
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