Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma

Predicting the outcome of immunotherapy treatment in melanoma patients is challenging. Alterations in genes involved in antigen presentation and the interferon gamma (IFNγ) pathway play an important role in the immune response to tumors. We describe here that the overexpression of PSMB8 and PSMB9, t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Kalaora, Shelly, Lee, Joo Sang, Barnea, Eilon, Levy, Ronen, Greenberg, Polina, Alon, Michal, Yagel, Gal, Bar Eli, Gitit, Oren, Roni, Peri, Aviyah, Patkar, Sushant, Bitton, Lital, Rosenberg, Steven A., Lotem, Michal, Levin, Yishai, Admon, Arie, Ruppin, Eytan, Samuels, Yardena
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021791/
https://ncbi.nlm.nih.gov/pubmed/32060274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14639-9
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