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Mesenchymal stromal cell derived CCL2 is required for accelerated wound healing

Mesenchymal stromal cells (MSC) have immunomodulatory effects impacting macrophages, promoting polarisation towards a reparative phenotype. CCL2 is a potent cytokine involved in the recruitment of macrophages. We hypothesised that MSC derived CCL2 may be involved in the MSC therapeutic effect by fac...

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Pubblicato in:Sci Rep
Autori principali: Whelan, Derek S., Caplice, Noel M., Clover, Anthony J. P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021763/
https://ncbi.nlm.nih.gov/pubmed/32060374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59174-1
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