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PARP Inhibitors in Prostate and Urothelial Cancers
Poly(ADP-ribose) polymerase (PARP) inhibitors targeting DNA repair gene mutations have shown significant clinical benefit in patients with ovarian and breast cancers. In metastatic prostate cancers, the prevalence of DNA repair gene mutations is up to 20%, and early phase studies have shown clinical...
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| Publicado no: | Front Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7020773/ https://ncbi.nlm.nih.gov/pubmed/32117762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00114 |
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