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Inhibition of NADPH Oxidase 5 (NOX5) Suppresses High Glucose-Induced Oxidative Stress, Inflammation and Extracellular Matrix Accumulation in Human Glomerular Mesangial Cells

BACKGROUND: The aim of this study was to explore the effects of NADPH oxidase 5 (NOX5) in high glucose-stimulated human glomerular mesangial cells (HMCs). MATERIAL/METHODS: Cells were cultured under normal glucose (NG) or high glucose (HG) conditions. Then, NOX5 siRNA was transfected into HG-treated...

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Veröffentlicht in:Med Sci Monit
Hauptverfasser: Li, Yingxin, Li, Yarong, Zheng, Shouhao
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Scientific Literature, Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020764/
https://ncbi.nlm.nih.gov/pubmed/32012145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.919399
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