Maternal Inulin Supplementation Alters Hepatic DNA Methylation Profile and Improves Glucose Metabolism in Offspring Mice

SCOPE: As a prebiotic, inulin may have a protective effect on glucose metabolism. However, the mechanism of inulin treatment on glucose intolerance in offspring exposed to a maternal high-fat (HF) diet is still not clear. Here, we examined the hepatic DNA methylation profile to determine how materna...

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Опубликовано в: :Front Physiol
Главные авторы: Zhang, Qian, Xiao, Xinhua, Zheng, Jia, Li, Ming, Yu, Miao, Ping, Fan, Wang, Tong, Wang, Xiaojing
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Physiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020697/
https://ncbi.nlm.nih.gov/pubmed/32116778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00070
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