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Sustainable ppm level palladium-catalyzed aminations in nanoreactors under mild, aqueous conditions

A 1 : 1 Pd : ligand complex, [t-BuXPhos(Pd-π-cinnamyl)]OTf, has been identified as a highly robust pre-catalyst for amination reactions leading to diarylamines, where loadings of metal are typically at 1000 ppm Pd, run in water at temperatures between rt and 45 °C. The protocol is exceptionally simp...

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Dettagli Bibliografici
Pubblicato in:Chem Sci
Autori principali: Zhang, Yitao, Takale, Balaram S., Gallou, Fabrice, Reilly, John, Lipshutz, Bruce H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020654/
https://ncbi.nlm.nih.gov/pubmed/32110341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03710a
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