Glutaminase 1 Regulates Neuroinflammation After Cerebral Ischemia Through Enhancing Microglial Activation and Pro-Inflammatory Exosome Release

Cerebral ischemia induces a robust neuroinflammatory response that is largely mediated by the activation of CNS resident microglia. Activated microglia produce pro-inflammatory molecules to cause neuronal damage. Identifying regulators of microglial activation bears great potential in discovering pr...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Gao, Ge, Li, Congcong, Zhu, Jie, Wang, Yi, Huang, Yunlong, Zhao, Shu, Sheng, Shiyang, Song, Yu, Ji, Chenhui, Li, Chunhong, Yang, Xiaoyu, Ye, Ling, Qi, Xinrui, Zhang, Yanyan, Xia, Xiaohuan, Zheng, Jialin C.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020613/
https://ncbi.nlm.nih.gov/pubmed/32117296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00161
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