Using toponomics to characterize phenotypic diversity in alveolar macrophages from male mice treated with exogenous SP-A1

BACKGROUND: We used the Toponome Imaging System (TIS) to identify “patterns of marker expression”, referred to here as combinatorial molecular phenotypes (CMPs) in alveolar macrophages (AM) in response to the innate immune molecule, SP-A1. METHODS: We compared 114 AM from male SP-A deficient mice. O...

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Detalles Bibliográficos
Publicado en:Biomark Res
Main Authors: Phelps, David S., Chinchilli, Vernon M., Weisz, Judith, Shearer, Debra, Zhang, Xuesheng, Floros, Joanna
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020580/
https://ncbi.nlm.nih.gov/pubmed/32082572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-019-0181-z
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