Using the LN34 Pan-Lyssavirus Real-Time RT-PCR Assay for Rabies Diagnosis and Rapid Genetic Typing from Formalin-Fixed Human Brain Tissue

Human rabies post mortem diagnostic samples are often preserved in formalin. While immunohistochemistry (IHC) has been routinely used for rabies antigen detection in formalin-fixed tissue, the formalin fixation process causes nucleic acid fragmentation that may affect PCR amplification. This study r...

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Detaylı Bibliyografya
Yayımlandı:Viruses
Asıl Yazarlar: Condori, Rene Edgar, Niezgoda, Michael, Lopez, Griselda, Matos, Carmen Acosta, Mateo, Elinna Diaz, Gigante, Crystal, Hartloge, Claire, Filpo, Altagracia Pereira, Haim, Joseph, Satheshkumar, Panayampalli Subbian, Petersen, Brett, Wallace, Ryan, Olson, Victoria, Li, Yu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Case Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019996/
https://ncbi.nlm.nih.gov/pubmed/31963651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12010120
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