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A Polymorphism in the Catalase Gene Promoter Confers Protection against Severe RSV Bronchiolitis

Respiratory syncytial virus (RSV) infection is associated with oxidative lung injury, decreased levels of antioxidant enzymes (AOEs), and the degradation of the transcription factor NF-E2-related factor 2 (NRF2), a master regulator of AOE expression. Single nucleotide polymorphisms (SNPs) in AOE and...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Chambliss, Jeffrey M., Ansar, Maria, Kelley, John P., Spratt, Heidi, Garofalo, Roberto P., Casola, Antonella
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019864/
https://ncbi.nlm.nih.gov/pubmed/31947722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12010057
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