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Viral-mediated Inhibition of Antioxidant Enzymes Contributes to the Pathogenesis of Severe Respiratory Syncytial Virus Bronchiolitis

Rationale: Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections in children, for which no specific treatment or vaccine is currently available. We have previously shown that RSV induces reactive oxygen species in cultured cells and oxidative injury in the lungs of...

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Detalhes bibliográficos
Main Authors: Hosakote, Yashoda M., Jantzi, Paul D., Esham, Dana L., Spratt, Heidi, Kurosky, Alexander, Casola, Antonella, Garofalo, Roberto P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137144/
https://ncbi.nlm.nih.gov/pubmed/21471094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201010-1755OC
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