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Statin-Related Myotoxicity: A Comprehensive Review of Pharmacokinetic, Pharmacogenomic and Muscle Components

Statins are a cornerstone in the pharmacological prevention of cardiovascular disease. Although generally well tolerated, a small subset of patients experience statin-related myotoxicity (SRM). SRM is heterogeneous in presentation; phenotypes include the relatively more common myalgias, infrequent m...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Turner, Richard Myles, Pirmohamed, Munir
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019839/
https://ncbi.nlm.nih.gov/pubmed/31861911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9010022
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