Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics

The Ebola virus (EBOV) envelope glycoprotein (GP) mediates the fusion of the virion membrane with the membrane of susceptible target cells during infection. While proteolytic cleavage of GP by endosomal cathepsins and binding of the cellular receptor Niemann-Pick C1 protein (NPC1) are essential step...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Viruses
Egile Nagusiak: Durham, Natasha D., Howard, Angela R., Govindan, Ramesh, Senjobe, Fernando, Fels, J. Maximilian, Diehl, William E., Luban, Jeremy, Chandran, Kartik, Munro, James B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019799/
https://ncbi.nlm.nih.gov/pubmed/31952255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12010103
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