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Detailed Characteristics of Tonsillar Tumors with Extrachromosomal or Integrated Form of Human Papillomavirus

The human papillomavirus (HPV) integration, the critical step in viral carcinogenesis, most frequently occurs in the E2 gene, which results in its inactivation and in an increase of E6/E7 transcription. However, in a substantial number of tumors, the virus is present in an extrachromosomal form. For...

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Detalles Bibliográficos
Publicado en:Viruses
Main Authors: Pokrývková, Barbora, Saláková, Martina, Šmahelová, Jana, Vojtěchová, Zuzana, Novosadová, Vendula, Tachezy, Ruth
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019694/
https://ncbi.nlm.nih.gov/pubmed/31905862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12010042
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