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Detailed Characteristics of Tonsillar Tumors with Extrachromosomal or Integrated Form of Human Papillomavirus

The human papillomavirus (HPV) integration, the critical step in viral carcinogenesis, most frequently occurs in the E2 gene, which results in its inactivation and in an increase of E6/E7 transcription. However, in a substantial number of tumors, the virus is present in an extrachromosomal form. For...

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Bibliographic Details
Published in:Viruses
Main Authors: Pokrývková, Barbora, Saláková, Martina, Šmahelová, Jana, Vojtěchová, Zuzana, Novosadová, Vendula, Tachezy, Ruth
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019694/
https://ncbi.nlm.nih.gov/pubmed/31905862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12010042
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