The R251K Substitution in Viral Protein PB2 Increases Viral Replication and Pathogenicity of Eurasian Avian-like H1N1 Swine Influenza Viruses

The Eurasian avian-like swine (EA) H1N1 virus has affected the Chinese swine industry, and human infection cases have been reported occasionally. However, little is known about the pathogenic mechanism of EA H1N1 virus. In this study, we compared the mouse pathogenicity of A/swine/Guangdong/YJ4/2014...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Cai, Mengkai, Zhong, Ruting, Qin, Chenxiao, Yu, Zhiqing, Wen, Xiaoyan, Xian, Junsi, Chen, Yongjie, Cai, Yu, Yi, Heyou, Gong, Lang, Zhang, Guihong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019279/
https://ncbi.nlm.nih.gov/pubmed/31906472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12010052
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