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The R251K Substitution in Viral Protein PB2 Increases Viral Replication and Pathogenicity of Eurasian Avian-like H1N1 Swine Influenza Viruses

The Eurasian avian-like swine (EA) H1N1 virus has affected the Chinese swine industry, and human infection cases have been reported occasionally. However, little is known about the pathogenic mechanism of EA H1N1 virus. In this study, we compared the mouse pathogenicity of A/swine/Guangdong/YJ4/2014...

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Foilsithe in:Viruses
Main Authors: Cai, Mengkai, Zhong, Ruting, Qin, Chenxiao, Yu, Zhiqing, Wen, Xiaoyan, Xian, Junsi, Chen, Yongjie, Cai, Yu, Yi, Heyou, Gong, Lang, Zhang, Guihong
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019279/
https://ncbi.nlm.nih.gov/pubmed/31906472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12010052
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