Overexpression of microRNA-9 enhances cisplatin sensitivity in hepatocellular carcinoma by regulating EIF5A2-mediated epithelial-mesenchymal transition

We investigated the role of microRNA (miR)-9 in modulating chemoresistance in hepatocellular carcinoma (HCC) cells. MiR-9 was overexpressed or knocked down in HCC cell lines. Cell viability, cell proliferation, the expression of EIF5A2 and the epithelial-mesenchymal transition (EMT)-related proteins...

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Bibliographic Details
Published in:Int J Biol Sci
Main Authors: Bao, Ying, Zhang, Yibo, Lu, Yongliang, Guo, Huihui, Dong, Zhaohuo, Chen, Qiuqiang, Zhang, Xilin, Shen, Weiyun, Chen, Wei, Wang, Xiang
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2020
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019138/
https://ncbi.nlm.nih.gov/pubmed/32071552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.32460
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