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C-phycocyanin attenuates RANKL-induced osteoclastogenesis and bone resorption in vitro through inhibiting ROS levels, NFATc1 and NF-κB activation

Excessive bone loss occurs in inflammatory disorders such as periodontitis and osteoporosis. The underlying mechanism is related to the differentiation of macrophages into multinucleated giant osteoclasts and their bone resorptive activity. C-Phycocyanin (C-PC) is a phycobiliprotein extracted from t...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: AlQranei, Mohammed S., Aljohani, Hanan, Majumdar, Sunipa, Senbanjo, Linda T., Chellaiah, Meenakshi A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018981/
https://ncbi.nlm.nih.gov/pubmed/32054921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59363-y
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