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Identification of sequence-specific interactions of the CD44-intracellular domain with RUNX2 in the transcription of matrix metalloprotease-9 in human prostate cancer cells

Aim: The Cluster of differentiation 44 (CD44) transmembrane protein is cleaved by γ-secretase, the inhibition of which blocks CD44 cleavage. This study aimed to determine the biological consequence of CD44 cleavage and its potential interaction with Runt-related transcription factor (RUNX2) in a seq...

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Publicado en:Cancer Drug Resist
Autores principales: Senbanjo, Linda T., AlJohani, Hanan, AlQranei, Mohammed, Majumdar, Sunipa, Ma, Tao, Chellaiah, Meenakshi A.
Formato: Artigo
Lenguaje:Inglês
Publicado: OAE Publishing Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556329/
https://ncbi.nlm.nih.gov/pubmed/33062960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20517/cdr.2020.21
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