Silencing MYH9 blocks HBx-induced GSK3β ubiquitination and degradation to inhibit tumor stemness in hepatocellular carcinoma

MYH9 has dual functions in tumors. However, its role in inducing tumor stemness in hepatocellular carcinoma (HCC) is not yet determined. Here, we found that MYH9 is an effective promoter of tumor stemness that facilitates hepatocellular carcinoma pathogenesis. Importantly, targeting MYH9 remarkably...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Signal Transduct Target Ther
Hoofdauteurs: Lin, Xian, Li, Ai-min, Li, Yong-Hao, Luo, Rong-Cheng, Zou, Yu-Jiao, Liu, Yi-Yi, Liu, Chen, Xie, Ying-Ying, Zuo, Shi, Liu, Zhan, Liu, Zhen, Fang, Wei-Yi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018736/
https://ncbi.nlm.nih.gov/pubmed/32296025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-0111-4
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items