Encephalitic Alphaviruses Exploit Caveola-Mediated Transcytosis at the Blood-Brain Barrier for Central Nervous System Entry

Venezuelan and western equine encephalitis viruses (VEEV and WEEV, respectively) invade the central nervous system (CNS) early during infection, via neuronal and hematogenous routes. While viral replication mediates host shutoff, including expression of type I interferons (IFN), few studies have add...

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Pubblicato in:mBio
Autori principali: Salimi, Hamid, Cain, Matthew D., Jiang, Xiaoping, Roth, Robyn A., Beatty, Wandy L., Sun, Chengqun, Klimstra, William B., Hou, Jianghui, Klein, Robyn S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018649/
https://ncbi.nlm.nih.gov/pubmed/32047126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02731-19
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