Virus entry and replication in the brain precedes blood-brain barrier disruption during intranasal alphavirus infection

Viral infections of the central nervous system (CNS) are often associated with blood-brain barrier (BBB) disruption, yet the impact of virus replication and immune cell recruitment on BBB integrity are incompletely understood. Using two-photon microscopy, we demonstrate that Venezuelan equine enceph...

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Detalhes bibliográficos
Publicado no:J Neuroimmunol
Main Authors: Cain, Matthew D., Salimi, Hamid, Gong, Yongfeng, Yang, Lihua, Hamilton, Samantha L., Heffernan, James R., Hou, Jianghui, Miller, Mark J., Klein, Robyn S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694394/
https://ncbi.nlm.nih.gov/pubmed/28501330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2017.04.008
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