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Knock-in mice expressing an ethanol-resistant GluN2A NMDA receptor subunit show altered responses to ethanol

BACKGROUND: N-methyl-D-aspartate receptors (NMDARs) are glutamate-activated, heterotetrameric ligand-gated ion channels critically important in virtually all aspects of glutamatergic signaling. Ethanol inhibition of NMDARs is thought to mediate specific actions of ethanol during acute and chronic ex...

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發表在:Alcohol Clin Exp Res
Main Authors: Zamudio, Paula A., Smothers, Thetford C., Homanics, Gregg E., Woodward, John J.
格式: Artigo
語言:Inglês
出版: 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018579/
https://ncbi.nlm.nih.gov/pubmed/31872888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14273
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