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Regulation of neutrophil function by selective targeting of glycan epitopes expressed on the integrin CD11b/CD18

Polymorphonuclear neutrophils (PMN) play a critical role in the innate immune response to invading pathogens. However, dysregulated mucosal trafficking of PMN and associated epithelial tissue damage is a pathological hallmark of numerous inflammatory conditions including inflammatory bowel disease....

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Enregistré dans:
Détails bibliographiques
Publié dans:FASEB J
Auteurs principaux: Kelm, Matthias, Lehoux, Sylvain, Azcutia, Veronica, Cummings, Richard D., Nusrat, Asma, Parkos, Charles A., Brazil, Jennifer C
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018557/
https://ncbi.nlm.nih.gov/pubmed/31907993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902542R
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