Targeting epithelium-expressed sialyl Lewis glycans improves colonic mucosal wound healing and protects against colitis

Dysregulated healing of injured mucosa is a hallmark of many pathological conditions, including inflammatory bowel disease. Mucosal injury and chronic intestinal inflammation are also associated with alterations in epithelial glycosylation. Previous studies have revealed that inflammation-induced gl...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Kelm, Matthias, Quiros, Miguel, Azcutia, Veronica, Boerner, Kevin, Cummings, Richard D., Nusrat, Asma, Brazil, Jennifer C., Parkos, Charles A.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406298/
https://ncbi.nlm.nih.gov/pubmed/32427587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135843
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